Articles and Researches

Articles and Researches | Books

Chapter 1: Phytonutrients in the Treatment of Gastrointestinal Cancer

Chapter 1: Phytonutrients in the Treatment of Gastrointestinal Cancer
writer :
-
author :
Fatemeh Abbaszadeh, Sajad Fakhri, Sana Piri and Haroon Khan
Translator :
-
year of publication :
Apr 2 2024
Publishers :
Bentham Books

Cancers of the gastrointestinal tract (GIT) are the most common human malignancies. The prevalence of esophageal Cancer, pancreatic ductal adenocarcinoma, gastric Cancer, hepatocellular carcinoma, colorectal Cancer and gallbladder Cancer are on the rise now a days. Despite advances in cancer treatment, increasing reports are focusing on finding novel therapies with lower side effects and higher potency. From the mechanistic point of view, several dysregulated factors are behind the pathophysiology of GIT cancers. Multiple studies have shown molecular targeted therapies in various GIT cancers, including epidermal growth factor receptor pathway (EGFR), vascular endothelial growth factor pathway (VEGF), Wnt/β-catenin pathway, and insulin-like growth factor receptor (IGFR).The aforementioned mediators are the critical targets of the existence of monoclonal antibodies and small molecules in treating GIT cancers. Accordingly, providing the exact dysregulated mechanisms behind GIT cancers could pave the road in the treatment of cancers. This chapter reveals dysregulated signaling pathways and potential therapeutic agents in the treatment of GIT cancer.

 

Apr 2 2024
the latest

Articles and Researches

- Books
Chapter 1: Phytonutrients in the Treatment of Gastrointestinal Cancer
Chapter 1: Phytonutrients in the Treatment of Gastrointestinal Cancer

Articles and Researches

- New Published
Orexin receptors in the hippocampal dentate gyrus modulated the restraint stress induced analgesia in the animal model of chroni
Orexin receptors in the hippocampal dentate gyrus modulated the restraint stress induced analgesia in the animal model of chroni

Articles and Researches

- High IF
Endocannabinoid system as a therapeutic target for psychostimulants relapse: A systematic review of preclinical studies
Endocannabinoid system as a therapeutic target for psychostimulants relapse: A systematic review of preclinical studies